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Bioactive Food Components: Changing the Scientific Basis for Intake Recommendations

21 July 2022

This publication proposes a new framework for recommended intake, enabling the incorporation of aspects of basic, pre-clinical and clinical research – including the Evidence Based Medicine approach of Randomized Controlled Trials (RCT) – but allowing for decision-making based not primarily on RCT but on the totality of the evidence. It suggests the need for human intervention studies of a smaller scale than those used to evaluate drug efficacy and safety, arguing that RCT used to establish the safety and efficacy of drugs is, alone, not an appropriate method for establishing recommended intakes for nutrients and other bioactive substances. Click here to download the publication (PDF).


Disclaimer: This is a linked article to the International Alliance of Dietary/Food Supplement Associations (IADSA), of which the ASEAN Alliance of Health Supplement Associations (AAHSA) is a member of. MADSA is a member organisation of AAHSA. The full copyright of this publication belongs solely to IADSA.

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